Author’s response to reviews Title: Prevalence of Epstein-Barr virus DNA and Porphyromonas gingivalis in Japanese periimplantitis patients Authors:
نویسندگان
چکیده
We have considered each point raised by the reviewers and have revised the manuscript accordingly. A list of the changes, addressing the reviewer’s points, can be found below. (We highlighted the changes within the document by using red colored text). Of note, some of the points made would require additional experiments, which are currently being addressed in ongoing studies. Since their inclusion would increase the length of this manuscript beyond a reasonable length, we believe it is better that we complete this work as part of a follow-up study.
منابع مشابه
Prevalence of Epstein-Barr virus DNA and Porphyromonas gingivalis in Japanese peri-implantitis patients
BACKGROUND Peri-implantitis (PI) is an inflammatory reaction associated with functional deterioration of supporting bones around the dental implant. Recent studies suggested Epstein-Barr virus (EBV) is involved in the pathogenesis of periodontitis. We investigated the association between EBV and Porphyromonas gingivalis in Japanese PI patients. METHODS Fifteen periodontally healthy individual...
متن کاملHigher Prevalence of Epstein–Barr Virus DNA in Deeper Periodontal Pockets of Chronic Periodontitis in Japanese Patients
Periodontitis, a complex chronic inflammatory disease caused by subgingival infection, is among the most prevalent microbial diseases in humans. Although traditional microbiological research on periodontitis has focused on putative bacteria such as Porphyromonas gingivalis, the herpes virus is proposed to be involved in the pathogenesis of periodontitis because bacterial etiology alone does not...
متن کاملStudy on the association of Epstein - Barr virus with breast cancer in Khorramabad breast cancer patients, Iran
Background: Breast cancer is one of the most common malignancies in the world, and early diagnosis of this cancer is a key factor in its treatment. This cancer is a multi-stage disease, in which viruses can play a role. EBV is known as an important factor in the development of some human cancers. Therefore, this study was conducted to determine the relationship between Epstein-Barr virus, EBV, ...
متن کاملAnalysis of Epstein Barr Virus Genome in Serum and Ocular Samples of Patients with Inflammatory Eye Disease Using PCR Method
Background and Aims: Epstein-Barr virus (EBV) infection is very common in the population. Virus belongs to the family Herpesviridae, whose representatives are characterized by the ability to cause the human body latent persistent infections. The goal of this study was to assess EBV infection frequency using PCR method in samples from inflammatory eye disease, in comparison with EBV presence in ...
متن کاملRelationship between Porphyromonas gingivalis, Epstein-Barr virus infection and reactivation in periodontitis.
The aim of this study was to assess the relationship-between Porphyromonas gingivalis, Epstein-Barr virus (EBV) infection and reactivation in periodontitis using real-time PCR. The mean proportion of P. gingivalis cells to total bacterial cells in the saliva from EBV-positive periodontitis patients was significantly higher than that in saliva from EBV-negative patients. An EBV-positive B-cell l...
متن کامل